Vial Filler and Capper

Vial filler and capper (automated vial filler) preform filling, stoppering and cap sealing of pharmaceutical glass vials. For precise filling, the machine has an SS 316L filling pump that was specially designed. Turntable, stainless steel slat conveyor belt, and special eccentric pre-, filling, and post-gassing comprise the vial filler and sealer machine. 316L stainless steel syringes that are incredibly accurate and efficient, non-toxic synthetic rubber tubing, and a compact, easily accessible panel.

The risk of contamination is decreased by keeping the distance between the stoppering units and the vial filling low. The devices are intended to be used under laminar flow protection and in sterile environments. The un-scrambler has undergone redesign in order to get rid of troublesome areas and dead ends. Dosage vials ranging from 2 ml to 250 ml can be filled using an injectable liquid filler. There are machines available that range in production output from 20 VPM to 300 VPM, from lab/pilot scale to production scale.

Vial Filler and Capper Machine Video

Salient Features of  Vial Filler and Capper

• Compact footprint cGMP complied models.
• 2ml to 250ml fill dosage compatibility.
• Filling accuracy of ±1% depends upon fluid & vial types.
• “No Vial – No Filling” system feature.
• In-feed Turn Table/ Unscrambler attached with the machine for automatic feeding of vials.
• All Contact Parts Made from AISI SS 316L & framework by AISI SS 304.
• No cross contamination.
• Easy to validate filling system for small/large batch production.
• Variable A.C. frequency drive for speed adjustment.
• Digital Vial Counter for counting production output.
• On-line Mechanism.
• IQ/OQ validation documents can be offered.
• PLC system with Graphical User Interface. (Optional)

Process Operation of Vial Filling and Capping

The incoming dry vials (sterilized and siliconized) are fed through the unscrambler and suitably guided on the moving Delrin slat conveyor belt at the required speed of the correct placement below filling unit.

The filling unit consists of Filling Head, Syringes & Nozzles; Syringes & Nozzles are made of AISI SS 316L materials. A Star Wheel is provided which holds the vial during filling operation. A sensor is provided for ”No Vial-No Filling” operation. Syringes are mounted on eccentric block and driving through bottom main gear box. Volume can be increase & decrease by increasing or decreasing stroke length of piston as per filling size. Syringes is having non return valve for sucking and delivering situation to avoid volume variation. Liquid reaches to filling nozzles through silicon transparent pipe. Nozzles having up & down movement with help of cam mechanism, and it come down when vial hold by starwheel for filling operation and starts filling when it starts to move up and after completion of filling operation, starwheel delivers two vials together on conveyor for rubber stoppering operation.

Stoppering unit consist of Star wheel, Vibrator unit and Bowl. The sterilized and siliconized rubber stoppers stored in the vibrator bowl moves vertically to the rubber stopper chute. The vial is hold firmly by starwheel, which will be in continuous rotary motion and vial which is coming from filling unit get in to starwheel and move in rotary direction along with starwheel, during movement it picks up the rubber stopper from the exit end of the chute and rubber stopper pressed by fix single pressing roller, which is spring loaded. Then vial further move on conveyor and collected on out feed starwheel for next sealing operation.

Technical Specification of  Vial Filler and Capper

* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.