Vial Powder Filling & Rubber Stoppering Machine including injectable powder filling machine perform precise filling operation of powder injection vials. Machine encompasses Turn Table for loading, Conveyor for transportation, Powder Wheel for powder filling, Stoppering Unit for rubber stoppering operations. All assemblies connected with each other to make one complete synchronize operations. Eight ports make up Vial Dry Powder Filling Machine that is automatic. Access doors allow maintenance personnel to service the machine within the stainless steel sheets around the expertly welded steel frame. The Automatic Single Wheel Vial Powder Filling & Stoppering Machine from Adinath can produce up to 7000 vials per hour, while the Automatic Double Wheel Vial Powder Filling & Stoppering Machine can produce up to 14,000 vials per hour. Every contact part is manufactured in accordance with current good manufacturing practice (cGMP) and is intended for excellent housekeeping.
Adinath is one of the leading vial powder filling machine manufacturers in India with customer base in 48 countries. Our range of vial filling machines are working in leading pharmaceutical companies. We also provide vial washing machine, vial cap sealing machine and vial sticker labeling machine to make one complete vial powder filling line. We provide IQ, OQ, DQ validation protocols for the supplied machines. Upon specific request we can offer 21 CFR part 11 automation package . We can offer you CE mark machine model upon specific requirement production.
Vial Powder Filling & Rubber Stoppering Machine Video
Salient Features of Vial Powder Filling & Rubber Stoppering Machine
- Compact cGMP model.
- “No Vial, No Filling” system eliminates wastage of costly powder.
- Multiple Dosing System.
- High Volumetric Filling Accuracy of ±2% of uniform density Injectable powder can be ensured by setting the depth of piston in the port of powder wheel.
- Built-in Rubber Stoppering Unit saves lot of space in the Sterile Area & reduces the length of Laminar Flow.
- Individual drive for the filling & sealing to match the speed of filling & sealing.
- All motors are provided with appropriate contractors and relays for the protection against any overload or jamming.
- Safety clutch system to avoid Vial breakage.
- Variable AC Frequency Drive for speed adjustment.
- All contact parts are easily removable for mandatory Autoclaving/ Sterilization.
- Digital counter for counting production output.
Working Principle of Vial Powder Filler
The sterilized powder is stored in powder hopper is agitated by pair of mechanical agitators for maintaining consistency and uniform bulk density. The powder wheel having eight ports rotates at the pre determined speed below the powder hopper with practically no clearance. Powder wheel consist of Piston in each port and behind the powder wheel vacuum plate is provided there is no clearance between powder wheel and vacuum plate due to back spring pressure. Precise volume of powder is sucked in to the port of powder wheel during vacuum according to the piston length different fill size can be achieved. The excess powder is doctored off by a doctor blade. Doctor blades can be adjusted from outside also without removing powder hopper. When powder wheel indexes further and remain in the port due to the vacuum till it reaches just vertically above the container. The time dose of Compressed air (Nitrogen Gas), sterilized low pressure air sequentially flushes out powder from the port of powder wheel in to the container one by one. The filled containers are immediately separated on the conveyor by vial separator and moves further for stoppering operation. (Different grooves separator can be used which depends on the container diameter or multiple dosing systems). The sterilized, siliconised, rubber stoppers stored in the vibrator bowl moves to vibratory bowl and stacked vertically in the rubber stopper chute. The container is hold firmly between pair or timing belt to pickup rubber stopper from exit end of the chute. Further the container is passed between two pressing roller for tight fit fixing of rubber stopper.
Technical Specification of Vial Powder Filling & Rubber Stoppering Machine
| Models | APF 12S | APF 12D |
| Production Output | Up to 100 vials/minute | Up to 200 vials/minute |
| Fill Volume | 50 mg. to 10grams | 50 mg. to 10 grams |
| Vial Size | 5ml to 250ml | 5ml to 250ml |
| Filling Accuracy | ± 2 – 3% in single dosing depending upon consistency and uniformity of bulk density of Injectable Powder | ± 2 – 3% in single dosing depending upon consistency and uniformity of bulk density of Injectable Powder |
| Power Load | 3.5 H. P. | 4.5 H. P. |
| Overall Dimension | 2600mm (L) X 1100mm (W) X 1800mm (H) approx. | 3000mm (L) X 1100mm (W) X 1800mm (H) approx. |
| Net Weight | 500 kgs. approx. | 700 kgs. approx. |
| Gross Weight | 750 kgs. approx. | 950 kgs. approx. |
* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.
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