The Injectable Liquid Filling and Rubber Stoppering Machine serves pharmaceutical, biotech and life‑science manufacturers. It doses sterile liquids into glass vials and seats butyl rubber stoppers in one sealed flow. It reduces manual steps and the risk of contamination. Users benefit from consistent volumes, secure seals, daily quick audits, simplified training and easy integration into clean‑room lines.
Injectable Liquid Filling and Rubber Stoppering Machine Video
Types of Injectable Liquid Filling Machines
SS 304 Durability, Precision Filling and Vacuum Stoppering
The Injectable Liquid Filling and Rubber Stoppering Machine is constructed on an MS frame made of polished SS 304 with all product‑contact parts in SS 316L. It can withstand daily wash‑downs and autoclave cycles without corrosion. A compact turntable feeds vials under diving‑type nozzles, which fill each vial from the bottom up to prevent foam and spills. Stainless‑steel piston syringes or peristaltic pumps deliver volumes from 2 ml to 100 ml with ±1 % accuracy. Immediately after filling, a vacuum‑assisted stoppering head seats each butyl stopper for an airtight seal. Modular panels and tool‑free parts make format swaps and cleaning fast, so you minimise downtime while upholding strict cGMP standards.
How Does the Liquid Filling and Stoppering Machine Work
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Vial Feeding: You load sterilised vials; the worm and star wheel space them under each filling head.
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Liquid Filling: Pistons draw and dose liquid from the hopper into each vial with ±1 % accuracy.
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Rubber Stoppering: A vibratory bowl feeds stoppers; a vacuum‑powered head locks each one tight.
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Safety Monitoring: Sensors watch pressure, vacuum and stopper fit; the line pauses at any hitch.
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Discharge: Sealed vials roll upright onto the outfeed table, ready for labelling or packing.
Key Features
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No vial, no fill: The system holds off dosing until every vial is in place, so you never lose product.
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SS 316L parts: All liquid‑touching surfaces resist corrosion and autoclave sterilisation.
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Bottom‑up filling: Diving nozzles fill under liquid to cut foam and spills.
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±1 % accuracy: Syringes or pumps deliver precise volumes every cycle.
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Vacuum stoppering: Seats stoppers under vacuum for a perfect, leak‑proof seal.
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Variable speed drives: Match fill and conveyor speeds to your line’s pace.
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Quick‑release guards: Panels and hopper lift off in seconds for a thorough clean.
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Tool‑free change parts: Swap guide rails, nozzles and stoppers in minutes.
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Half‑stoppering option: Seat stoppers halfway when required for secondary processes.
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Live data logging: Watch fill counts, weights and any pauses in real time—perfect for quick audits.
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On‑the‑go checks: Pull vials for quality checks without ever stopping the machine.
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Automatic safeguards: Emergency stops and alarms leap into action at the first sign of trouble.
Technical Specification of Injectable Liquid Filling Machine
| Models | ALVF‑40 | ALVF‑80 | ALVF‑120 | ALVF‑250 |
| No. of Heads | 2 heads | 4 heads | 8 heads | 12 heads |
| Output Rate | Up to 40 Vials/Minute | Up to 80 Vials/Minute | Up to 150 Vials/Minute | Up to 250 Vials/Minute |
| Fill Range | 2 ml – 100 ml via syringe or peristaltic pump. | 2 ml – 100 ml via syringe or peristaltic pump. | 2 ml – 100 ml via syringe or peristaltic pump. | 2 ml – 100 ml via syringe or peristaltic pump. |
| Accuracy | ±1 % at humidity up to 28 % RH. | ±1 % at humidity up to 28 % RH. | ±1 % at humidity up to 28 % RH. | ±1 % at humidity up to 28 % RH. |
| Vial Size | Diameter 15 – 70 mm; height 25 – 140 mm. | Diameter 15 – 70 mm; height 25 – 140 mm. | Diameter 15 – 70 mm; height 25 – 140 mm. | Diameter 15 – 70 mm; height 25 – 140 mm. |
| Stopper Size | 13 mm & 20 mm butyl rubber | 13 mm & 20 mm butyl rubber | 13 mm & 20 mm butyl rubber | 13 mm & 20 mm butyl rubber |
| Construction | SS 304 frame; SS 316L wetted parts; non‑toxic tubing. | SS 304 frame; SS 316L wetted parts; non‑toxic tubing. | SS 304 frame; SS 316L wetted parts; non‑toxic tubing. | SS 304 frame; SS 316L wetted parts; non‑toxic tubing. |
| Power | 220 VAC, 3 HP; 50 Hz; custom voltages available. | 220 VAC, 3 HP; 50 Hz; custom voltages available. | 220 VAC, 3 HP; 50 Hz; custom voltages available. | 220 VAC, 3 HP; 50 Hz; custom voltages available. |
| Air Supply | 4 bar filtered, oil‑free compressed air. | 4 bar filtered, oil‑free compressed air. | 4 bar filtered, oil‑free compressed air. | 4 bar filtered, oil‑free compressed air. |
| Vacuum | 28 inHg at 500 LPM. | 28 inHg at 500 LPM. | 28 inHg at 500 LPM. | 28 inHg at 500 LPM. |
| Conveyor Height | Adjustable 800 – 850 mm. | Adjustable 800 – 850 mm. | Adjustable 800 – 850 mm. | Adjustable 800 – 850 mm. |
| Dimensions | 2050 × 850 × 1700 mm (L × W × H). | 2200mm (L) x 850mm (W) x 1700mm (H) | 3000mm (L) x 945mm (W) x 1700mm (H) | 3500mm (L) x 945mm (W) x 1700mm (H) |
* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.
The Injectable Liquid Filling and Rubber Stoppering Machine gives you a seamless, high‑capacity solution for vial filling and capping. Its stainless‑steel frame, diving‑type filling, and vacuum stoppering ensure precise volumes and airtight seals at top speed. Quick‑release panels, tool‑free parts and clever safety interlocks shave hours off cleaning and maintenance. Integrated logging gives you a clear record of every fill and pause. This machine ramps up throughput, reduces rejects and lets your team spend time on product quality.
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