The Automatic Ampoule Filling and Sealing Machine PLC Model works best for pharma, biotech, veterinary, cosmetic and speciality‑chemical plants that need sealed ampoules for sterile doses. Its touch‑screen PLC sets fill volume, nitrogen flow and flame heat in seconds and stores recipes for later. The machine feeds, gases, fills, heats and flame‑seals ampoules in one enclosed line, keeping air out and meeting cGMP rules. It fits isolators or laminar‑air cabinets, installs quickly and records every step for audits. Users get fast change‑overs, dosing within ±1 %, fewer rejects and a stream of sterile, tamper‑proof ampoules ready for inspection, labelling or packing. Real‑time alarms and batch reports simplify validation, cut downtime and give proof to regulators and clients with confidence.
Automatic Ampoule Filling and Sealing Machine Video
Rugged Build, PLC‑Level Precision, Oxygen‑Safe Sealing
The Automatic Ampoule Filling and Sealing Machine PLC Model has a strong stainless‑steel frame (SS 304) and SS 316L contact parts, so it lasts for years and handles wash‑downs with ease. Flame guards and gas meters protect staff. The PLC watches piston, servo, or peristaltic pumps and keeps each dose within ±1 % while letting you change the fill size on the screen mid‑run, making it ideal for trial runs and 24/7 production output. Nitrogen gas covers the liquid before, during, and after filling to stop oxidation, and a pre‑heat station dries the glass so the LPG‑oxygen burner makes a clean seal. The machine turns out up to 200 ampoules a minute, and a “No Ampoule–No Fill” sensor stops spills, giving you fast, accurate, low‑reject production.
How Does the Automatic Ampoule Filling and Sealing Machine PLC Model Work
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Hopper Feed – Operators pour sterilised ampoules into a slanted hopper. A star wheel releases each ampoule onto a moving rack.
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Nitrogen Pre‑Flush – The first nozzle injects inert gas to push air out of the ampoule neck.
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Fill Cycle – A second nozzle dispenses liquid; the PLC keeps volume within the programmed set‑point, and sensors skip empty pockets.
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Nitrogen Post‑Flush – A third nozzle adds a protective blanket over the product.
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Pre‑Heat Stage – Low flame warms the glass, drives off moisture, and prepares the neck for sealing.
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Flame Seal & Discharge – A high‑heat burner melts the neck as rotating holders spin the ampoule for an even dome. The sealed unit falls onto a stainless tray for further examination.
Key Features
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PLC+HMI Panel – It stores several recipes, makes volume adjustments, and logs alarms on one screen.
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Auto Volume Adjust – Adjust fill volume from 1 litre to 2 litres in seconds, no tools or cams required.
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Multi‑Size Compatibility – Processes 1 ml–20 ml (single & twin head) or 1 ml–10 ml (four, six & eight head) ampoules.
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Nitrogen Flushing – Inert‑gas purge before, during, and after filling boosts product shelf life.
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Pre‑Warming Station – Heats glass for secure, particle‑free flame sealing.
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Short Change‑Overs – Quick‑swap holders and touch‑screen settings cut downtime between sizes.
Technical Specification of Automatic Ampoule Filler Machine
| Model | AFS-1 | AFS-2 | AFS-4 | AFS-8 |
| No. of Head | Single | Two | Four | Eight |
| Syringes | One | Double | Four | Eight |
| Ampoule Sizes | 1 ml to 30 ml | 1 ml to 30 ml | 1 ml to 20 ml | 1 ml to 20 ml |
| Filling Speed | Up to 25 ampoules/minute | Up to 50 ampoules/minute | Up to 100 ampoules/minute | Up to 200 ampoules/minute |
| Filling Precision | ± 1% | ± 1% | ± 1% | ± 1% |
| Filling Pump | Piston Pump | Piston Pump | Piston Pump | Piston Pump |
| Burner Gas | LPG & Oxygen (O₂) | LPG & Oxygen (O₂) | LPG & Oxygen (O₂) | LPG & Oxygen (O₂) |
| Nitrogen Arrangement | Before & After Filling | Before & After Filling | Before & After Filling | Before & After Filling |
| Number of Fill Nozzles | One | Two | Four | Eight |
| Number of Nitrogen Nozzles | Two | Four | Eight | Sixteen |
| Number of Sealing Burners | Two | Four | Eight | Sixteen |
| Power Required | 0.5 H.P. | 1 H.P. | 1 H.P. | 2 H.P. |
| Power Voltage | 230 Volts, Single Phase, 50 Hertz, 4 Wire System | 230 Volts, Single Phase, 50 Hertz, 4 Wire System | 230 Volts, Single Phase, 50 Hertz, 4 Wire System | 230 Volts, Single Phase, 50 Hertz, 4 Wire System |
| Contact Parts | Made from Stainless Steel 316L | Made from Stainless Steel 316L | Made from Stainless Steel 316L | Made from Stainless Steel 316L |
| Overall Dimension | 915mm (L) x 610mm (W) x 965mm (H) approx. | 915mm (L) x 760mm (W) x 965mm (H) approx. | 1200mm (L) x 1070mm (W) x 965mm (H) approx. | 2200mm (L) x 1400mm (W) x 1100mm (H) approx. |
* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.
The Automatic Ampoule Filling and Sealing Machine PLC Model lets you govern fill volumes, gas flows, and burner heat with a tap, then repeats those settings batch after batch. Stainless‑steel hardware withstands harsh sanitisers, while PLC alarms flag any deviation before it becomes waste. Choose the head count that fits your output, slot the machine into your sterile suite, and trust it to deliver airtight, oxygen‑free ampoules every shift—keeping production steady and regulators satisfied.
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