The High Speed Ampoule Filling & Sealing Machine meets the needs of pharmaceutical, biotechnology and cosmetic manufacturers for rapid, sterile ampoule production. It handles washed, sterile glass ampoules, pre‑gasses, fills, post‑gasses, pre‑heats and seals. This is a compact, cGMP‑compliant unit that reduces manual steps, cuts contamination risk and keeps your line running at full speed.
High Speed Ampoule Filling and Sealing Machine Video
Types of Ampoule Filling Machines
We have wide range of ampoule filling machines in product portfolio such as:
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Semi Automatic Ampoule Filling Machine
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Ampoule Sealing Machine
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Open Mouth Ampoule Filling Machine
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Laboratory Ampoule Filling Machine
Stainless Steel Robustness, Precision Filling and Maximum Throughput
The High Speed Ampoule Filling & Sealing Machine is built of a robust SS 304 frame with SS 316L contact parts, so you can blast it with sanitisers or hose it down without a hint of rust. Its modular layout puts each dosing syringe at your fingertips. The brushless motors drive them all to within 1 % accuracy, even with thick liquids. A built‑in pre‑warm station strips out moisture before sealing. Together, these features keep the production line running with almost no downtime.
How Does the Ampoule Filling & Sealing Machine Work
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Ampoule Infeed: You load sterilised ampoules onto a wire‑mesh belt; a turntable and cassette send eight into the star wheel.
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Pre‑gassing: Ampoules glide through a nitrogen tunnel that strips out oxygen and preserves your formula.
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Filling: Brushless syringes meter 1–10 ml into each ampoule with rock‑solid 1 % accuracy.
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Post‑gassing & Pre‑heat: A second nitrogen flush and a quick warm‑plate pass remove moisture for perfect seals.
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Sealing: LPG and oxygen flames shape the ampoule tip in one go; flow meters help you fine‑tune the burn.
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Discharge: Sealed ampoules land upright in a stainless tray, ready to inspect or pack—no touch required.
Key Features
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High throughput: You fill up to 200 ampoules a minute, perfect for large batches.
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cGMP compliant: Built to meet EU GMP and FDA standards so you can trust every batch.
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All‑stainless build: SS 304 frame and SS 316L parts take CIP and SIP without a flinch.
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Modular heads: Choose one, two, four or eight filling stations to suit your line.
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±1 % accuracy: Each ampoule hits the right level, whether you run small or large fills.
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Nitrogen purge: You remove air before, during and after filling to protect sensitive formulations.
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No ampoule, no fill: The interlock halts dosing if a vial is absent, so you save powder.
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On‑the‑go sampling: Grab ampoules for QC checks without pausing the line.
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Fast changeovers: Swap trays, nozzles and parts in minutes to keep production moving.
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Pre‑heat station: A quick heat blast dries ampoules before sealing for neat, smooth tips.
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Flame control: Tweak LPG and oxygen settings to achieve perfect, leak‑free seals every run.
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Safety first: Emergency stop and alarms protect operators and alert you to issues.
Technical Highlights
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Syringes: AISI 316L, gasket‑free, brushless motor drive
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Fill Volume: Adjustable 1 ml–10 ml per ampoule
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Gas Nozzles: Two per head for filling; burners match head count for sealing
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Pre‑warming: Integrated station with adjustable temperature
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Utilities: Efficient water and air usage; nitrogen supply for purging
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Compliance: CE marking; IQ/OQ documentation available on request
Technical Specification of Ampoule Filling and Sealing Machine
| Model | AFS-1 | AFS-2 | AFS-4 | AFS-8 |
| No. of Head | Single | Two | Four | Eight |
| Syringes | One | Double | Four | Eight |
| Ampoule Sizes | 1 ml to 30 ml | 1 ml to 30 ml | 1 ml to 20 ml | 1 ml to 20 ml |
| Filling Speed | Up to 25 ampoules/minute | Up to 50 ampoules/minute | Up to 100 ampoules/minute | Up to 200 ampoules/minute |
| Filling Precision | ± 1% | ± 1% | ± 1% | ± 1% |
| Filling Pump | Piston Pump | Piston Pump | Piston Pump | Piston Pump |
| Burner Gas | LPG & Oxygen (O₂) | LPG & Oxygen (O₂) | LPG & Oxygen (O₂) | LPG & Oxygen (O₂) |
| Nitrogen Arrangement | Before & After Filling | Before & After Filling | Before & After Filling | Before & After Filling |
| Number of Fill Nozzles | One | Two | Four | Eight |
| Number of Nitrogen Nozzles | Two | Four | Eight | Sixteen |
| Number of Sealing Burners | Two | Four | Eight | Sixteen |
| Power Required | 0.5 H.P. | 1 H.P. | 1 H.P. | 2 H.P. |
| Power Voltage | 230 Volts, Single Phase, 50 Hertz, 4 Wire System | 230 Volts, Single Phase, 50 Hertz, 4 Wire System | 230 Volts, Single Phase, 50 Hertz, 4 Wire System | 230 Volts, Single Phase, 50 Hertz, 4 Wire System |
| Contact Parts | Made from Stainless Steel 316L | Made from Stainless Steel 316L | Made from Stainless Steel 316L | Made from Stainless Steel 316L |
| Overall Dimension | 915mm (L) x 610mm (W) x 965mm (H) approx. | 915mm (L) x 760mm (W) x 965mm (H) approx. | 1200mm (L) x 1070mm (W) x 965mm (H) approx. | 2200mm (L) x 1400mm (W) x 1100mm (H) approx. |
* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.
This High Speed Ampoule Filling & Sealing Machine serves up precision and reliability in one compact unit. Its robust stainless‑steel frame, accurate dosing and airtight sealing keep your line running fast with hardly any waste. It ensures every ampoule seals accurately in every batch.
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